Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | HTR6 | P50406 | 15/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530503 | 0.91 | CYP3A4 (0.83) | CYP3A4CYP2D6HTR6L3MBTL1CA12 | |
| SCHEMBL6532617 | 0.89 | CYP3A4 (0.79) | CYP3A4CYP2D6HTR6L3MBTL1CA2 | |
| SCHEMBL6529121 | 0.85 | CYP3A4 (0.74) | CYP3A4CYP2D6HTR6DRD2HTR2A | |
| SCHEMBL6528817 | 0.83 | CYP3A4 (0.71) | CYP3A4CYP2D6HTR6L3MBTL1HTR2A | |
| SCHEMBL6530751 | 0.78 | CYP3A4 (0.64) | CYP3A4CYP2D6HTR6DRD2HTR2A | |
| SCHEMBL5251999 | 0.78 | HTR6 (0.78) | CYP3A4CYP2D6HTR6L3MBTL1CA12 | |
| SCHEMBL6529490 | 0.75 | CYP3A4 (0.60) | CYP3A4CYP2D6HTR6HTR2A | |
| SCHEMBL3644542 | 0.75 | HTR6 (1.00) | CYP3A4CYP2D6HTR6L3MBTL1CA12 | |
| SCHEMBL6529028 | 0.74 | HTR6 (0.60) | CYP3A4CYP2D6HTR6DRD2HTR2A | |
| SCHEMBL6528108 | 0.74 | HTR6 (0.60) | CYP3A4CYP2D6HTR6DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | claimed |
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | disclosed |