Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.83 |
| ▸ | HTR6 | P50406 | 17/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527092 | 0.91 | CYP3A4 (1.00) | CYP3A4CYP2D6HTR6L3MBTL1CA12 | |
| SCHEMBL6532617 | 0.87 | CYP3A4 (0.79) | CYP3A4CYP2D6HTR6L3MBTL1CA2 | |
| SCHEMBL6529028 | 0.84 | HTR6 (0.60) | CYP3A4CYP2D6HTR6 | |
| SCHEMBL6528817 | 0.80 | CYP3A4 (0.71) | CYP3A4CYP2D6HTR6L3MBTL1 | |
| SCHEMBL6529121 | 0.77 | CYP3A4 (0.74) | CYP3A4CYP2D6HTR6 | |
| SCHEMBL6530751 | 0.76 | CYP3A4 (0.64) | CYP3A4CYP2D6HTR6 | |
| SCHEMBL4673875 | 0.76 | HTR6 (1.00) | CYP3A4CYP2D6HTR6 | |
| SCHEMBL6529490 | 0.74 | CYP3A4 (0.60) | CYP3A4CYP2D6HTR6 | |
| SCHEMBL6528108 | 0.73 | HTR6 (0.60) | CYP3A4CYP2D6HTR6 | |
| SCHEMBL5353003 | 0.73 | HTR6 (1.00) | CYP3A4CYP2D6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | disclosed |