Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905425 | 0.87 | ACE (0.41) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL4963186 | 0.85 | ACE (0.40) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL27718628 | 0.85 | ACE (0.40) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL16761709 | 0.85 | L3MBTL1 (0.37) | ACE | |
| SCHEMBL3360876 | 0.77 | ACE (0.46) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL7113056 | 0.77 | ACE (0.46) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL10905654 | 0.76 | TSHR (0.39) | ACEREN | |
| SCHEMBL22418322 | 0.76 | ACE (0.35) | ACE | |
| SCHEMBL29586626 | 0.75 | GABRP (0.36) | ACEREN | |
| SCHEMBL7850459 | 0.72 | ALDH1A1 (0.41) | ACERENHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176801-A1 | Acyl bicyclic derivatives of pyrrol | GLAXO GROUP LIMITED (GB) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176801-A1 | Acyl bicyclic derivatives of pyrrol | NR1H3, NR1H2, NR1H4 | ACE 4000/4885REN 1328/4885LMNA 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.