Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 5/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905425 | 0.84 | ACE (0.41) | HSD17B10ACEREN | |
| SCHEMBL16761709 | 0.82 | L3MBTL1 (0.37) | ALDH1A1ACE | |
| SCHEMBL27718628 | 0.82 | ACE (0.40) | HSD17B10ACEREN | |
| SCHEMBL4963186 | 0.82 | ACE (0.40) | HSD17B10ACEREN | |
| SCHEMBL2902847 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7113056 | 0.75 | ACE (0.46) | HSD17B10ACEREN | |
| SCHEMBL3360876 | 0.75 | ACE (0.46) | HSD17B10ACEREN | |
| SCHEMBL6528047 | 0.72 | ACE (0.33) | HSD17B10ACEREN | |
| SCHEMBL20456353 | 0.71 | NOTUM (0.42) | ALDH1A1POLBGAA | |
| SCHEMBL4112477 | 0.70 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923287-A4 | NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES | LILLY CO ELI (US) | 2001-08-01 | — | — | EP | disclosed |
| EP-0923287-A1 | NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES | ELI LILLY AND COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008382-A1 | NONCLASSICAL PYRROLO[2,3-D]PYRIMIDINE ANTIFOLATES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |