Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376788 | 0.90 | ALDH1A1 (0.47) | PKMALDH1A1NPSR1TP53L3MBTL1 | |
| SCHEMBL5364296 | 0.87 | HSD17B10 (0.48) | GAAPKMALDH1A1L3MBTL1HPGD | |
| SCHEMBL18700972 | 0.78 | PRKAB2 (0.48) | GAAPKMALDH1A1NPSR1TP53 | |
| Hydrochloric Acid SCHEMBL27854427 | 0.77 | PRKAB2 (0.47) | GAAPKMALDH1A1NPSR1TP53 | |
| SCHEMBL29651902 | 0.76 | TRPV4 (0.49) | PKMALDH1A1NPSR1TP53L3MBTL1 | |
| SCHEMBL289253 | 0.76 | TRPV4 (0.49) | PKMALDH1A1NPSR1TP53L3MBTL1 | |
| SCHEMBL29908556 | 0.75 | CA2 (0.49) | GAAALDH1A1NPSR1TP53L3MBTL1 | |
| SCHEMBL289788 | 0.75 | CA2 (0.49) | GAAALDH1A1NPSR1TP53L3MBTL1 | |
| SCHEMBL16316790 | 0.73 | SMN1; SMN2 (0.65) | GAAPKMALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL28909093 | 0.72 | L3MBTL1 (0.68) | ALDH1A1NPSR1TP53L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023762-A1 | PYRROLIDINE-2-CARBONITRILE DERIVATIVES AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2005-03-17 | — | — | WO | disclosed |