Sugi Predict

Sugi Predict / Compounds / SCHEMBL289788

SCHEMBL289788

SCHEMBL289788

COc1ccc(Cl)c(S(N)(=O)=O)c1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 11/20 0.49
▸ CA1 P00915 4/20 0.49
▸ CA9 Q16790 4/20 0.49
▸ CA12 O43570 3/20 0.49
▸ STAT3 P40763 1/20 0.47
▸ ALDH1A1 P00352 2/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ GAA P10253 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ TP53 P04637 1/20 0.44
▸ CA3 P07451 1/20 0.44
▸ CA4 P22748 1/20 0.44
▸ CA6 P23280 1/20 0.44
▸ CA5A P35218 1/20 0.44
▸ CA7 P43166 1/20 0.44
▸ CA14 Q9ULX7 1/20 0.44
▸ CA5B Q9Y2D0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908556 1.00 CA2 (0.49) CA2CA1CA9CA12STAT3
SCHEMBL21800161 0.85 CA2 (0.49) CA2CA1CA9CA12ALDH1A1
SCHEMBL29651902 0.83 TRPV4 (0.49) ALDH1A1L3MBTL1NPSR1TP53
SCHEMBL5376788 0.83 ALDH1A1 (0.47) ALDH1A1L3MBTL1NPSR1TP53
SCHEMBL289253 0.83 TRPV4 (0.49) ALDH1A1L3MBTL1NPSR1TP53
SCHEMBL18700972 0.81 PRKAB2 (0.48) ALDH1A1L3MBTL1GAAMAPTNPSR1
SCHEMBL940166 0.81 MMP2 (0.60) CA2CA1STAT3ALDH1A1L3MBTL1
SCHEMBL29469939 0.80 PDIA6 (0.51) CA2CA1CA9CA12STAT3
Hydrochloric Acid SCHEMBL27854427 0.80 PRKAB2 (0.47) ALDH1A1L3MBTL1GAAMAPTNPSR1
SCHEMBL8295570 0.79 ALDH1A1 (0.51) CA2CA1CA9CA12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777129-A Synthesis method of trifluramide 利民化学有限责任公司 2024-03-29 — — CN claimed
US-20220153734-A1 Pyrazolopyridine Compounds For IRE1 Inhibition Optikira, LLC 2022-05-19 — — US claimed
EP-2766362-B1 SOLID FORMS OF NEMATOCIDAL SULFONAMIDES DU PONT (US) 2018-04-11 — — EP claimed
US-9040554-B2 Solid forms of nematocidal sulfonamides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-05-26 — — US claimed
EP-2766362-A1 SOLID FORMS OF NEMATOCIDAL SULFONAMIDES E. I. Du Pont de Nemours and Company (US) 2014-08-20 — — EP claimed
US-20140228393-A1 SOLID FORMS OF NEMATOCIDAL SULFONAMIDES CORTEVA AGRISCIENCE LLC 2014-08-14 — — US claimed
WO-2013055584-A1 SOLID FORMS OF NEMATOCIDAL SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-04-18 — — WO claimed
US-20250129031-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD (IN) 2025-04-24 — — US disclosed
CN-119219808-A Multifunctional ionic polymer, preparation method and application thereof, and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 — — CN disclosed
EP-4469442-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF PI Industries Ltd. (IN) 2024-12-04 — — EP disclosed
CN-118696033-A 1,2, 3-Triazole carbonyl sulfonamide compound and application thereof PI工业有限公司 2024-09-24 — — CN disclosed
CN-117777129-A Synthesis method of trifluramide 利民化学有限责任公司 2024-03-29 — — CN disclosed
CN-117777129-A Synthesis method of trifluramide 利民化学有限责任公司 2024-03-29 — — CN disclosed
US-20130190172-A1 NEMATOCIDAL SULFONAMIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2013-07-25 — — US disclosed
WO-2013055584-A1 SOLID FORMS OF NEMATOCIDAL SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-04-18 — — WO disclosed
WO-2013055584-A1 SOLID FORMS OF NEMATOCIDAL SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-04-18 — — WO disclosed
US-20120114624-A1 NEMATOCIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-10 — — US disclosed
WO-2012054233-A1 NEMATOCIDAL SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-04-26 — — WO disclosed
EP-2427058-A2 NEMATOCIDAL SULFONAMIDES E. I. du Pont de Nemours and Company (US) 2012-03-14 — — EP disclosed
WO-2010129500-A2 NEMATOCIDAL SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129031-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF GLP1R, CBR3, CBR1 CA2 853/4885CA1 2681/4885CA9 1740/4885
US-20140228393-A1 SOLID FORMS OF NEMATOCIDAL SULFONAMIDES MSL1, MLN, ABCG2 CA2 1328/4885CA1 1109/4885CA9 2710/4885
US-20130190172-A1 NEMATOCIDAL SULFONAMIDES QSOX1, ARSA, NOX1 CA2 190/4885CA1 102/4885CA9 294/4885
US-20120114624-A1 NEMATOCIDAL SULFONAMIDES NSFL1C, QSOX1, Q6ZSR9 CA2 923/4885CA1 990/4885CA9 1178/4885
US-20220153734-A1 Pyrazolopyridine Compounds For IRE1 Inhibition XBP1, ERN1, ERN2 CA2 4235/4885CA1 4705/4885CA9 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.