Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528870 | 0.88 | NOTUM (0.39) | MAPTALDH1A1TP53GAACYP4F2 | |
| SCHEMBL6530940 | 0.86 | KMT2A (0.39) | THRBMAPTLMNATSHRALDH1A1 | |
| SCHEMBL6509824 | 0.86 | CYP4F2 (0.34) | RXFP1ALDH1A1NPSR1GLAGAA | |
| SCHEMBL6528363 | 0.80 | MAPT (0.38) | THRBMAPTRXFP1LMNATSHR | |
| SCHEMBL6527238 | 0.79 | NPSR1 (0.45) | MAPTLMNAALDH1A1NPSR1GAA | |
| SCHEMBL6502389 | 0.76 | ALDH1A1 (0.38) | THRBALDH1A1NPSR1GAACYP4F2 | |
| SCHEMBL6532465 | 0.67 | MAPT (0.41) | THRBMAPTRXFP1LMNATSHR | |
| SCHEMBL6528531 | 0.66 | NOTUM (0.46) | MAPTALDH1A1NPSR1GAACYP4F2 | |
| SCHEMBL6529673 | 0.65 | ALDH1A1 (0.49) | MAPTTSHRALDH1A1TP53GAA | |
| SCHEMBL15157526 | 0.65 | KMT2A (0.60) | THRBMAPTRXFP1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056536-A1 | ANTIDIABETIC AGENTS WHICH EXHIBIT ACTIVITY AGAINST PPAR | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-23 | — | — | WO | disclosed |