Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508554 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAASMN1; SMN2HPGD | |
| SCHEMBL6509824 | 0.79 | CYP4F2 (0.34) | ALDH1A1GAASMN1; SMN2HPGDGSK3B | |
| SCHEMBL6528870 | 0.77 | NOTUM (0.39) | ALDH1A1KDM4EGAASMN1; SMN2CYP4F2 | |
| SCHEMBL6530940 | 0.77 | KMT2A (0.39) | ALDH1A1GAATHRBUSP2KMT2A | |
| SCHEMBL6527238 | 0.77 | NPSR1 (0.45) | ALDH1A1KDM4EGAASMN1; SMN2HPGD | |
| SCHEMBL6528744 | 0.76 | THRB (0.36) | ALDH1A1GAATHRBCYP4F2CYP4A11 | |
| SCHEMBL6530164 | 0.62 | PPARG (0.34) | ALDH1A1SMN1; SMN2NPSR1NPC1RAB9A | |
| SCHEMBL6508934 | 0.61 | KMT2A (0.33) | ALDH1A1CLCN2KMT2AHTT | |
| SCHEMBL6510219 | 0.59 | CYP4F2 (0.46) | ALDH1A1KDM4EGAAHPGDGSK3B | |
| SCHEMBL11068446 | 0.59 | CA12 (0.43) | ALDH1A1GAASMN1; SMN2NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056536-A1 | ANTIDIABETIC AGENTS WHICH EXHIBIT ACTIVITY AGAINST PPAR | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-23 | — | — | WO | disclosed |