Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509824 | 0.90 | CYP4F2 (0.34) | KMT2AMEN1ALDH1A1GAAPOLB | |
| SCHEMBL6528744 | 0.86 | THRB (0.36) | KMT2AALDH1A1TSHRLMNATHRB | |
| SCHEMBL6527238 | 0.86 | NPSR1 (0.45) | ALDH1A1HSD17B10LMNAGAAMAPT | |
| SCHEMBL6528870 | 0.83 | NOTUM (0.39) | KMT2AMEN1ALDH1A1TP53GAA | |
| SCHEMBL6529673 | 0.80 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1CBX7CDYL2 | |
| SCHEMBL6502389 | 0.77 | ALDH1A1 (0.38) | KMT2AALDH1A1USP2THRBHTT | |
| SCHEMBL6506652 | 0.69 | CYP4F2 (0.41) | KMT2AMEN1ALDH1A1HSD17B10LMNA | |
| SCHEMBL2627034 | 0.66 | USP2 (0.70) | KMT2AMEN1ALDH1A1CBX7CDYL2 | |
| SCHEMBL6528363 | 0.65 | MAPT (0.38) | KMT2AALDH1A1TSHRLMNATHRB | |
| SCHEMBL6530164 | 0.63 | PPARG (0.34) | KMT2AALDH1A1TP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056536-A1 | ANTIDIABETIC AGENTS WHICH EXHIBIT ACTIVITY AGAINST PPAR | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-23 | — | — | WO | disclosed |