Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282541 | 0.79 | DPP4 (0.40) | GPR119ALDH1A1HPGDSMN1; SMN2P2RX4 | |
| Hydrochloric Acid SCHEMBL6647135 | 0.79 | CHRNB2 (0.38) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL29504447 | 0.71 | DPP7 (0.47) | GPR119ALDH1A1HPGDSMN1; SMN2P2RX4 | |
| SCHEMBL6646237 | 0.71 | — | — | |
| SCHEMBL4562330 | 0.71 | TSHR (0.39) | GPR119ALDH1A1HPGDSMN1; SMN2P2RX4 | |
| SCHEMBL1713154 | 0.66 | PDE4B (0.35) | GPR119MMP1MMP9P2RX4BCHE | |
| SCHEMBL5412873 | 0.65 | ALDH1A1 (0.42) | GPR119ALDH1A1HPGDSMN1; SMN2FAAH | |
| SCHEMBL2654623 | 0.65 | TSHR (0.40) | GPR119ALDH1A1SMN1; SMN2FAAHPDE4B | |
| SCHEMBL1712728 | 0.64 | CA2 (0.43) | GPR119SMN1; SMN2TSHR | |
| SCHEMBL1713628 | 0.64 | GPR119 (0.39) | GPR119MMP1MMP9P2RX4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009392-A2 | DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-03 | — | — | WO | disclosed |