Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PARL | Q9H300 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733860 | 0.89 | CYP2C9 (0.53) | CYP2C9CYP3A4CYP2C19MMP2CYP2D6 | |
| SCHEMBL4005331 | 0.82 | MMP2 (0.59) | CYP2C19MMP2PKMMAPTPOLB | |
| SCHEMBL11584726 | 0.82 | MMP2 (0.59) | MMP2PKMMAPTPOLBALDH1A1 | |
| SCHEMBL5759490 | 0.80 | CYP3A4 (0.64) | CYP2C9CYP3A4CYP2C19MMP2CYP2D6 | |
| SCHEMBL2989085 | 0.75 | GFER (0.64) | CYP2C9CYP3A4CYP2C19MMP2CYP2D6 | |
| SCHEMBL6688886 | 0.73 | PKM (0.66) | CYP2C9CYP3A4CYP2C19MMP2CYP2D6 | |
| SCHEMBL3631733 | 0.73 | KMT2A (0.65) | PKMMAPTALDH1A1HTR6 | |
| SCHEMBL8972689 | 0.70 | ALDH1A1 (0.69) | CYP2C9CYP3A4CYP2C19MMP2CYP2D6 | |
| SCHEMBL7380549 | 0.70 | PKM (0.62) | CYP2C9CYP3A4CYP2C19MMP2CYP2D6 | |
| SCHEMBL14387374 | 0.70 | HTR6 (0.47) | CYP2C9CYP3A4CYP2C19CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032858-A1 | Novel heterocyclic compound and anti-inflamatory agent | NIPPON SODA CO., LTD. (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1435353-A1 | NOVEL HETEROCYCLIC COMPOUND AND ANTI-INFLAMMATORY AGENT | NIPPON SODA CO., LTD. (JP) | 2004-07-07 | — | — | EP | disclosed |
| US-5391757-A | Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| US-5338883-A | Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| US-5252539-A | Benzenesulfonyl carboxamide compounds intermediate compounds and method of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| US-5120854-A | Benzenesulfonyl carboxamide compounds and intermediate compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| US-4992094-A | Herbicides | AMERICAN CYANAMID COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4883914-A | Benzenesulfonyl carboxamide compounds useful as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4107304-A | Oxo-imidazolidine substituted cephalosporins and antibacterial compositions and methods of combatting bacteria employing them | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |
| US-4093722-A | ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4086340-A | ANTIBIOTIC; ANIMAL GROWTH PROMOTER | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-25 | — | — | US | disclosed |
| US-4009272-A | ANTIBIOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-22 | — | — | US | disclosed |
| US-3983105-A | Penicillins | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | disclosed |
| US-3978056-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |
| US-3975375-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |
| US-3974142-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3974141-A | IMIDAZOLIDINYL-CARBAMIDOBACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3972869-A | Penicillins | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
| US-3972870-A | IMIDAZOLIDINYL-CARBAMIDO-BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032858-A1 | Novel heterocyclic compound and anti-inflamatory agent | TLR5, IRF3, IL4 | CYP2C9 3393/4885CYP3A4 1019/4885CYP2C19 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.