Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ADA | P00813 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529330 | 0.78 | MEN1 (0.36) | MEN1KMT2APRKD1OPRM1 | |
| SCHEMBL19691308 | 0.68 | PRKD1 (0.35) | MEN1KMT2APRKD1OPRM1ALDH1A1 | |
| SCHEMBL6504137 | 0.62 | CPB2 (0.47) | MEN1KMT2AADA | |
| SCHEMBL18850919 | 0.61 | PSMB8 (0.54) | MEN1KMT2APSMB8PSMB9PSMB5 | |
| SCHEMBL18850877 | 0.61 | PSMB8 (0.54) | MEN1KMT2APSMB8PSMB9PSMB5 | |
| SCHEMBL3081871 | 0.61 | IRAK4 (0.40) | OPRM1 | |
| SCHEMBL4803883 | 0.60 | HCAR2 (0.36) | TP53ALDH1A1 | |
| SCHEMBL4023030 | 0.58 | WDR5 (0.36) | MEN1KMT2APSMB8PSMB5CNR1 | |
| SCHEMBL14605847 | 0.57 | MEN1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL507870 | 0.57 | PARP10 (0.65) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256167-A1 | Preparation and use of imidazole derivatives for treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256167-A1 | Preparation and use of imidazole derivatives for treatment of obesity | GPR119, GIPR, PGC | MEN1 1397/4885KMT2A 481/4885PRKD1 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.