Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268994 | 0.77 | WDR5 (0.36) | HCAR2HSD17B10GAAKDM4EALDH1A1 | |
| SCHEMBL30707793 | 0.68 | GABRA2 (0.46) | HCAR2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL773059 | 0.66 | S1PR1 (0.53) | RETS1PR1ALDH1A1TP53 | |
| SCHEMBL18040239 | 0.65 | RXFP1 (0.37) | HCAR2HSD17B10GAAKDM4EALDH1A1 | |
| SCHEMBL4026141 | 0.63 | MAPK1 (0.35) | RETGAAKDM4EALDH1A1 | |
| SCHEMBL6529330 | 0.61 | MEN1 (0.36) | HSD17B10GAA | |
| SCHEMBL771719 | 0.61 | S1PR1 (0.48) | S1PR1KDM4EALDH1A1TP53 | |
| SCHEMBL2327699 | 0.61 | CPB2 (0.47) | HSD17B10GAAKDM4EL3MBTL1 | |
| SCHEMBL28440995 | 0.61 | KMO (0.42) | HSD17B10GAAKDM4EL3MBTL1 | |
| SCHEMBL6529327 | 0.60 | MEN1 (0.36) | ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |