Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | OGFRL1 | Q5TC84 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529612 | 0.84 | CASP1 (0.60) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL2783456 | 0.79 | MAPK1 (0.56) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL3012671 | 0.78 | MAPK1 (0.55) | LMNAALDH1A1KDM4EHPGDCASP1 | |
| SCHEMBL2783058 | 0.78 | OGFRL1 (0.56) | ALDH1A1GAAKDM4ECASP1CASP7 | |
| SCHEMBL6581741 | 0.78 | CASP1 (0.57) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL29847379 | 0.78 | CASP1 (0.57) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL6505956 | 0.77 | PYGM (0.56) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL6503393 | 0.77 | HSD17B10 (0.62) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL2783060 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL6529824 | 0.76 | LMNA (0.62) | LMNAALDH1A1GAAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |