Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PYGM | P11217 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497804 | 0.90 | KDM4E (0.64) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL6532182 | 0.84 | KDM4E (0.77) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL6505494 | 0.84 | HSD17B10 (0.58) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL6504646 | 0.84 | HSD17B10 (0.58) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL6529548 | 0.84 | HSD17B10 (0.54) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL6529612 | 0.82 | CASP1 (0.60) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL6500237 | 0.82 | KDM4E (0.62) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL14470780 | 0.79 | PYGM (0.69) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL6529824 | 0.78 | LMNA (0.62) | HSD17B10CASP1CASP7L3MBTL1LMNA | |
| SCHEMBL5551592 | 0.78 | LMNA (0.62) | HSD17B10CASP1CASP7L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021547-A3 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD (AU) | 2005-08-18 | — | — | WO | disclosed |
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |