Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 8/20 | 1.00 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943034 | 0.89 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6533676 | 0.89 | HPSE (1.00) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6503052 | 0.83 | HPSE (0.87) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6506352 | 0.83 | HPSE (0.87) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6258154 | 0.83 | HPSE (0.81) | HPSEPRMT5 | |
| SCHEMBL6532513 | 0.83 | HPSE (0.87) | HPSEMMP2MMP9MMP8MMP13 | |
| SCHEMBL6244081 | 0.82 | PRMT5 (1.00) | HPSEPRMT5MMP2MMP9MMP8 | |
| SCHEMBL6528618 | 0.81 | HPSE (0.77) | HPSEPRMT5 | |
| SCHEMBL6506260 | 0.81 | MMP2 (0.93) | HPSEPRMT5MMP2MMP9MMP8 | |
| SCHEMBL27202475 | 0.81 | HPSE (0.73) | HPSEPRMT5MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042495-A1 | (BENZIMIDAZOL-2-YL)-PHENYL-PHENYL-UREA COMPOUNDS AND METHODS FOR INHIBITING HEPARANASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-05-12 | — | — | WO | disclosed |