Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731992 | 0.79 | LMNA (0.48) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| SCHEMBL4631540 | 0.77 | LMNA (0.56) | LMNASMN1; SMN2CES2CES1TSHR | |
| SCHEMBL27317647 | 0.77 | AKT1 (0.43) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| SCHEMBL693987 | 0.76 | SMN1; SMN2 (0.50) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| SCHEMBL8840365 | 0.76 | MAPT (0.40) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| SCHEMBL7111247 | 0.75 | MAOA (0.38) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| SCHEMBL3005533 | 0.75 | AKT1 (0.41) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL29028321 | 0.74 | SMN1; SMN2 (0.48) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| SCHEMBL16062547 | 0.74 | L3MBTL1 (0.54) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| Ethylene Glycol SCHEMBL12990057 | 0.72 | ALDH1A1 (0.37) | LMNAMAPTXBP1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050025729-A1 | Lipstick | BEIERSDORF AG | 2005-02-03 | — | — | US | disclosed |