Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133372 | 0.82 | CYP3A4 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7517167 | 0.80 | CYP3A4 (0.33) | ALDH1A1 | |
| SCHEMBL28432676 | 0.75 | PRKCI (0.36) | PRKCIAOC1AOC3KDM4EALDH1A1 | |
| SCHEMBL28058874 | 0.73 | PRKCI (0.43) | PRKCIKDM4EALDH1A1GLAGAA | |
| SCHEMBL6535376 | 0.73 | AOC1 (0.30) | AOC1AOC3 | |
| SCHEMBL10881335 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL8445395 | 0.72 | PRKCI (0.33) | PRKCIKDM4E | |
| SCHEMBL5082011 | 0.71 | ALDH1A1 (0.35) | PRKCIKDM4EALDH1A1GAA | |
| SCHEMBL3674257 | 0.69 | NOS2 (0.33) | — | |
| SCHEMBL27909752 | 0.69 | CYP3A4 (0.43) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037649-B1 | POLYMERIC PRODRUGS OF AMINO- AND HYDROXYL-CONTAINING BIOACTIVE AGENTS | ENZON INC (US) | 2009-09-30 | — | — | EP | disclosed |