SCHEMBL6535740

SCHEMBL6535740

NC(COCCO)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.55
NOS1 P29475 2/20 0.55
NOS2 P35228 2/20 0.55
PTGS1 P23219 1/20 0.41
SLC7A11 Q9UPY5 1/20 0.41
SLC1A1 P43005 4/20 0.40
SLC1A5 Q15758 1/20 0.40
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
SLC7A5 Q01650 2/20 0.38
GSR P00390 2/20 0.38
GRIK1 P39086 2/20 0.38
GRIK2 Q13002 2/20 0.38
GRM1 Q13255 2/20 0.38
GRM2 Q14416 2/20 0.38
SLC1A3 P43003 2/20 0.38
SLC1A2 P43004 2/20 0.38
GRM8 O00222 1/20 0.38
GRM6 O15303 1/20 0.38
GRIN2D O15399 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093094 1.00 NOS3 (0.55) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL617875 1.00 NOS3 (0.55) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL890468 0.96 NOS3 (0.51) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL890472 0.96 NOS3 (0.51) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL22091990 0.87 NOS3 (0.51) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL22091993 0.87 NOS3 (0.51) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL31688563 0.84 NOS3 (0.53) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL17434420 0.83 NOS3 (0.53) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL9423322 0.83 NOS3 (0.53) NOS3NOS1NOS2PTGS1SLC7A11
SCHEMBL8892097 0.83 NOS3 (0.53) NOS3NOS1NOS2PTGS1SLC7A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100513386-C Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils DOMP S P A (IT) 2009-07-15 CN claimed
CN-1205220-C Novel cyclosporins CHEM AG C (CH) 2005-06-08 CN claimed
CN-1479715-A Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils ��ķ�ɷ����޹�˾ 2004-03-03 CN claimed
CN-1305493-A Novel cyclosporins CHEM AG C (CH) 2001-07-25 CN claimed
US-20250250565-A1 OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES ALPHA ANOMERIC SAS (FR) 2025-08-07 US disclosed
CN-118256591-A Cyclic peptide compound having high membrane permeability and library comprising same 中外制药株式会社 2024-06-28 CN disclosed
CN-118184532-A Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same 中外制药株式会社 2024-06-14 CN disclosed
CN-113454058-B Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same 中外制药株式会社 2024-03-22 CN disclosed
CN-110869544-B Cyclic peptide compound having high membrane permeability and library comprising same 中外制药株式会社 2024-03-08 CN disclosed
US-20240002853-A1 NUCLEIC ACID DUPLEXES ALPHA ANOMERIC SAS (FR) 2024-01-04 US disclosed
US-11807664-B2 Method for producing cyclic organic compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-11-07 US disclosed
US-11807664-B2 Method for producing cyclic organic compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-11-07 US disclosed
WO-2019215333-A1 OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES ALPHA ANOMERIC SAS (FR) 2019-11-14 WO disclosed
CN-100513386-C Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils DOMP S P A (IT) 2009-07-15 CN disclosed
CN-1205220-C Novel cyclosporins CHEM AG C (CH) 2005-06-08 CN disclosed
EP-1282722-A4 STABILIZED PROTEINS AVATAR MEDICAL L L C (US) 2004-04-07 EP disclosed
CN-1479715-A Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils ��ķ�ɷ����޹�˾ 2004-03-03 CN disclosed
EP-1282722-A1 STABILIZED PROTEINS Avatar Medical, L.L.C. (US) 2003-02-12 EP disclosed
CN-1305493-A Novel cyclosporins CHEM AG C (CH) 2001-07-25 CN disclosed
WO-2001029247-A1 STABILIZED PROTEINS AVATAR MEDICAL, LLC (US) 2001-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002853-A1 NUCLEIC ACID DUPLEXES NOP2, NOP58, POLRMT NOS3 3715/4885NOS1 3230/4885NOS2 3650/4885
US-11807664-B2 Method for producing cyclic organic compound SCTR, CTRC, DCXR NOS3 282/4885NOS1 267/4885NOS2 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.