Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.64 |
| ▸ | GABRD | O14764 | 3/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.64 |
| ▸ | GABRE | P78334 | 3/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.64 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.64 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.64 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL2450977 | 1.00 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL28474785 | 0.86 | LMNA (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Bicarbonate SCHEMBL8854028 | 0.85 | — | — | |
| Bicarbonate SCHEMBL3833313 | 0.85 | ALDH1A1 (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL7086022 | 0.85 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL27563645 | 0.85 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Valeric Acid SCHEMBL29134031 | 0.84 | AKR1B1 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Glycine SCHEMBL8858281 | 0.83 | GLRA1 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Propionic Acid SCHEMBL11706355 | 0.83 | FFAR3 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Propionic Acid SCHEMBL29203841 | 0.83 | FFAR3 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103805202-B | Copper oxide etching solution and use its engraving method | 旭化成株式会社 | 2018-05-18 | — | — | CN | disclosed |
| US-9139771-B2 | Copper oxide etchant and etching method using the same | ASAHI KASEI E-MATERIALS CORPORATION (JP) | 2015-09-22 | — | — | US | disclosed |
| CN-102753651-B | Etching solution for copper oxide and etching method using same | ASAHI CHEMICAL IND | 2014-09-10 | — | — | CN | disclosed |
| CN-103805202-A | Copper Oxide Etchant And Etching Method Using The Same | ASAHI CHEMICAL IND | 2014-05-21 | — | — | CN | disclosed |
| US-20130026134-A1 | COPPER OXIDE ETCHANT AND ETCHING METHOD USING THE SAME | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2013-01-31 | — | — | US | disclosed |
| EP-2540801-A1 | COPPER OXIDE ETCHANT AND ETCHING METHOD USING THE SAME | Asahi Kasei Kabushiki Kaisha (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-6824968-B2 | IMPROVED COLOR REPRODUCTION, AND PARTICULARLY TO A COLOR REVERSAL PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL WHICH IS SUPERIOR IN SKIN COLOR REPRODUCTION | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-6682881-B2 | POLYOXYETHYLENE/POLYOXYPROPYLENE) COPOLYMER AS A SURFACE ACTIVE AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 2004-01-27 | — | — | US | disclosed |
| US-6656673-B2 | Color photography | FUJI PHOTO FILM CO., LTD. (JP) | 2003-12-02 | — | — | US | disclosed |
| US-6645680-B2 | A lightsensitive silver halide emulsion layer comprising silver iodide grains capable of imparting interimage effects | FUJI PHOTO FILM CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-20020025497-A1 | Silver halide color photographic light-sensitive material and color image formation method using the same | FUJIFILM CORPORATION (JP) | 2002-02-28 | — | — | US | disclosed |
| US-20020019566-A1 | Alkylation of amino acids | THE ASSOCIATED OCTEL COMPANY LIMITED | 2002-02-14 | — | — | US | disclosed |
| US-6278020-B1 | REACTING AMINO ACID WITH HALOGEN COMPOUND IN AQUEOUS MEDIUM TO FORM ALKYLATED AMINO ACID; RECOVERING UNREACTED AMINO ACID BY ACIDIFICATION TO CRYSTALLIZE PRODUCT; SEPARATION; NANOFILTRATION; RECYCLING | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 2001-08-21 | — | — | US | disclosed |
| US-6075164-A | REACTING WITH A DIHALOHYDROCARBYL COMPOUND IN AN AQUEOUS MEDIUM AT A PH IN THE RANGE 7-14 AND IN THE PRESENCE OF DISSOLVED CATIONS OF AN ALKALINE EARTH METAL OR A TRANSITION METAL | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 2000-06-13 | — | — | US | disclosed |
| EP-0765863-B1 | Alkylation of amino acids | ASS OCTEL (GB) | 2000-01-12 | — | — | EP | disclosed |
| US-5849948-A | Alkylation of amino acids | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |
| EP-0677037-B1 | ALKYLATION OF AMINO ACIDS | ASS OCTEL (GB) | 1998-04-08 | — | — | EP | disclosed |
| EP-0765863-A1 | Alkylation of amino acids | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1997-04-02 | — | — | EP | disclosed |
| EP-0677037-A1 | ALKYLATION OF AMINO ACIDS | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1995-10-18 | — | — | EP | disclosed |
| WO-1995012570-A2 | ALKYLATION OF AMINO ACIDS | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1995-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019566-A1 | Alkylation of amino acids | BCAT1, BCAT2, DAO | GABRP 540/4885GABRD 683/4885GABRA1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.