Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | KLK1 | P06870 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377282 | 0.84 | LIPE (0.51) | RAB9AALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL12020270 | 0.78 | LTA4H (0.52) | LMNAHTT | |
| SCHEMBL4762790 | 0.77 | CYP2C9 (0.39) | PTGS1AKR1C3AKR1C2RAB9ACA2 | |
| SCHEMBL384743 | 0.77 | GAA (0.57) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL6553235 | 0.77 | LMNA (0.55) | KDM4EPOLBRAB9AALDH1A1HSD17B10 | |
| SCHEMBL9733951 | 0.76 | KMT2A (0.51) | RAB9AALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL23751423 | 0.76 | SRD5A2 (0.58) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL10896825 | 0.76 | CA2 (0.49) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL10894946 | 0.76 | GAA (0.46) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL6137045 | 0.76 | HSD17B10 (0.39) | KDM4EPOLBPTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | KDM4E 2107/4885POLB 1231/4885PTGS1 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.