Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552730 | 0.88 | POLB (0.66) | POLBMAPTPKMLMNATAAR1 | |
| SCHEMBL6554514 | 0.88 | MTNR1B (0.41) | POLBMAPTPKMNAMPTMTNR1B | |
| SCHEMBL6540974 | 0.83 | ALDH1A1 (0.52) | LMNA | |
| SCHEMBL6553063 | 0.81 | KMT2A (0.47) | POLBMAPTPKMTAAR1SLC6A4 | |
| SCHEMBL6552531 | 0.81 | ESR1 (0.46) | POLBMAPTPKMNAMPTMTNR1B | |
| SCHEMBL6680807 | 0.81 | AKR1C3 (0.48) | POLB | |
| SCHEMBL6553968 | 0.81 | CYP4F2 (0.42) | POLBMAPTPKMNAMPTTAAR1 | |
| SCHEMBL6554093 | 0.81 | PNMT (0.43) | POLBMAPTPKMNAMPTTAAR1 | |
| SCHEMBL694663 | 0.80 | TAAR1 (0.63) | LMNACYP3A4TAAR1SLC6A4ACHE | |
| SCHEMBL694664 | 0.80 | TAAR1 (0.63) | LMNACYP3A4TAAR1SLC6A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |