Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403383 | 0.70 | SMN1; SMN2 (0.38) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9210090 | 0.68 | L3MBTL1 (0.40) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL21253055 | 0.65 | LMNA (0.44) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8836724 | 0.65 | L3MBTL1 (0.38) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6545896 | 0.64 | TDP1 (0.37) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6987805 | 0.64 | KMT2A (0.37) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8692714 | 0.64 | THRB (0.40) | LMNATHRBCA4 | |
| SCHEMBL343269 | 0.63 | SMN1; SMN2 (0.45) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1453001 | 0.63 | SMN1; SMN2 (0.45) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL5173197 | 0.63 | SMN1; SMN2 (0.45) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334095-A4 | PROCESS FOR THE PREPARATION OF PGD2 ANTAGONIST | SHIONOGI & CO (JP) | 2004-03-17 | — | — | EP | disclosed |
| EP-1334095-A1 | PROCESS FOR THE PREPARATION OF PGD2 ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032892-A1 | PROCESS FOR THE PREPARATION OF PGD2 ANTAGONIST | SHIONOGI & CO., LTD (JP) | 2002-04-25 | — | — | WO | disclosed |