Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545896 | 0.98 | TDP1 (0.37) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8428763 | 0.71 | MAOA (0.39) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL27911540 | 0.71 | LMNA (0.40) | L3MBTL1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL9210090 | 0.70 | L3MBTL1 (0.40) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21253055 | 0.67 | LMNA (0.44) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6542228 | 0.65 | TDP1 (0.37) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6987805 | 0.65 | KMT2A (0.37) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7219363 | 0.65 | LMNA (0.33) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL343269 | 0.64 | SMN1; SMN2 (0.45) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA | |
| SCHEMBL1453001 | 0.64 | SMN1; SMN2 (0.45) | L3MBTL1TDP1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62061987-A | — | — | None | — | — | JP | disclosed |
| US-5641784-A | ADENOSINE ANTAGONISTS; TREATMENT OF NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM KG (DE) | 1997-06-24 | — | — | US | disclosed |
| EP-0487673-A1 | NEW XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1992-06-03 | — | — | EP | disclosed |
| WO-1992000297-A1 | NEW XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1992-01-09 | — | — | WO | disclosed |
| JP-S6261987-A | PRODUCTION OF ACYLSILANE | SHIN ETSU CHEM CO LTD | 1987-03-18 | — | — | JP | disclosed |