Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8836724 | 0.98 | L3MBTL1 (0.38) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8428763 | 0.70 | MAOA (0.39) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27911540 | 0.70 | LMNA (0.40) | L3MBTL1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL9210090 | 0.68 | L3MBTL1 (0.40) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL21253055 | 0.65 | LMNA (0.44) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6542228 | 0.64 | TDP1 (0.37) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6987805 | 0.64 | KMT2A (0.37) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7219363 | 0.64 | LMNA (0.33) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL343269 | 0.63 | SMN1; SMN2 (0.45) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1453001 | 0.63 | SMN1; SMN2 (0.45) | TDP1L3MBTL1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420011-A1 | Compounds usefulfor treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1380571-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-0919544-B1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0633776-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-0919544-A1 | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5643946-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5614540-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5602157-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| US-5552438-A | Compounds useful for treating allergic and inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0633776-A4 | — | — | 1995-01-25 | — | — | EP | disclosed |
| EP-0633776-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993019749-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |