Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306685 | 0.86 | LMNA (0.63) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL257135 | 0.85 | LMNA (0.61) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL364764 | 0.85 | ALDH1A1 (0.65) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL30100412 | 0.85 | MRGPRX4 (0.64) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL48961 | 0.85 | MRGPRX4 (0.64) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7210817 | 0.83 | MRGPRX4 (0.62) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL726267 | 0.83 | MAPT (0.60) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL31207306 | 0.83 | MAPT (0.60) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL1095516 | 0.83 | MEN1 (0.64) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL29812845 | 0.83 | MEN1 (0.64) | LMNAKCNMA1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135119-A4 | GLUCOSE AND LIPID LOWERING COMPOUNDS | ALTEON INC (US) | 2004-11-03 | — | — | EP | disclosed |
| US-6509480-B2 | 4,7,8 alpha H-eudesma-5(6), 11(13)-dien-8, 12-olide derivatives | ALTEON, INC. | 2003-01-21 | — | — | US | disclosed |
| US-20020151581-A1 | Glucose and lipid lowering compounds | SYNVISTA THERAPEUTICS, INC. | 2002-10-17 | — | — | US | disclosed |
| US-6326396-B1 | ACID OR AMIDE COMPOUND ON HYDRONAPHTHALENE COMPOUND | ALTEON, INC. | 2001-12-04 | — | — | US | disclosed |
| EP-1135119-A1 | GLUCOSE AND LIPID LOWERING COMPOUNDS | ALTEON, INC. (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000027388-A1 | GLUCOSE AND LIPID LOWERING COMPOUNDS | ALTEON, INC. (US) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151581-A1 | Glucose and lipid lowering compounds | HMGCR, APOB, SREBF1 | LMNA 1061/4885KCNMA1 3911/4885ALDH1A1 1228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.