SCHEMBL6545119

SCHEMBL6545119

CCCCc1cc2ccccc2c(O)c1O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.47
TYR P14679 1/20 0.43
GPR84 Q9NQS5 1/20 0.42
MAPT P10636 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
USP2 O75604 1/20 0.40
GLA P06280 1/20 0.40
CYP3A4 P08684 1/20 0.40
GAA P10253 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
CASP6 P55212 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10933263 0.95 TLR8 (0.49) TLR8TYRMAPTKDM4EALDH1A1
SCHEMBL9643304 0.93 MAPT (0.49) TLR8TYRMAPTKDM4EALDH1A1
SCHEMBL17329242 0.89 GPR84 (0.51) GPR84KDM4EALDH1A1HPGDGAA
SCHEMBL10337577 0.87 TLR8 (0.45) TLR8TYRGPR84MAPTKDM4E
SCHEMBL887833 0.87 KDM4E (0.49) TLR8TYRKDM4EALDH1A1HPGD
SCHEMBL27814439 0.87 KDM4E (0.46) TLR8TYRGPR84KDM4EALDH1A1
Formic Acid SCHEMBL27795499 0.87 MAPT (0.47) TLR8TYRMAPTKDM4EALDH1A1
SCHEMBL3168425 0.83 ESR1 (0.52) TLR8GPR84MAPTKDM4EALDH1A1
SCHEMBL11126792 0.82 KDM4E (0.47) TLR8TYRMAPTKDM4EALDH1A1
SCHEMBL8760245 0.82 TYR (0.47) TLR8TYRMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597876-A CURING AGENT PROVIDES BETTER MECHANICAL PROPERTIES AT HIGH TEMPERATURE SHELL OIL COMPANY (US) 1997-01-28 US claimed
US-10723690-B2 (Meth)acryloyl compound and method for producing same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-07-28 US disclosed
US-20180210341-A1 NOVEL (METH)ACRYLOYL COMPOUND AND METHOD FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-07-26 US disclosed
EP-3326997-A1 NEW (METH)ACRYLOYL COMPOUND AND PRODUCTION METHOD FOR SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2018-05-30 EP disclosed
CN-104968637-B Allyl compound and its manufacture method 三菱瓦斯化学株式会社 2017-12-26 CN disclosed
EP-2955169-B1 NOVEL ALLYL COMPOUND AND METHOD FOR PRODUCING THE SAME MITSUBISHI GAS CHEMICAL CO (JP) 2017-03-15 EP disclosed
US-9464068-B2 Allyl compound and method for producing the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-10-11 US disclosed
US-20150368224-A1 NOVEL ALLYL COMPOUND AND METHOD FOR PRODUCING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-12-24 US disclosed
EP-2955169-A1 NOVEL ARYL COMPOUND AND METHOD FOR PRODUCING SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2015-12-16 EP disclosed
EP-1218178-B1 AN ADHESION PROMOTING LAYER FOR USE WITH EPOXY PREPREGS GA TEK INC (US) 2004-01-07 EP disclosed
EP-1218178-A4 AN ADHESION PROMOTING LAYER FOR USE WITH EPOXY PREPREGS GA TEK INC (US) 2003-01-08 EP disclosed
EP-1218178-A1 AN ADHESION PROMOTING LAYER FOR USE WITH EPOXY PREPREGS Ga-Tek Inc. (US) 2002-07-03 EP disclosed
WO-2001019607-A1 AN ADHESION PROMOTING LAYER FOR USE WITH EPOXY PREPREGS GA-TEK INC. (US) 2001-03-22 WO disclosed
US-6117536-A MULTILAYER STRUCTURE COMPRISING PREPREG LAYER MADE FROM EPOXY RESIN AND NON-AMINE CURING AGENT, NITROGEN-CONTAINING SILANE ADHESION PROMOTING LAYER GA-TEK INC. (US) 2000-09-12 US disclosed
EP-0720630-B1 EPOXY RESIN COMPOSITION SHELL INT RESEARCH (NL) 1999-03-17 EP disclosed
US-5597876-A CURING AGENT PROVIDES BETTER MECHANICAL PROPERTIES AT HIGH TEMPERATURE SHELL OIL COMPANY (US) 1997-01-28 US disclosed
EP-0720630-A1 EPOXY RESIN COMPOSITION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-07-10 EP disclosed
EP-0682052-A1 Composition of epoxy resins based on condensed polynuclear aromatic compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-11-15 EP disclosed
WO-1995008584-A1 EPOXY RESIN COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1995-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180210341-A1 NOVEL (METH)ACRYLOYL COMPOUND AND METHOD FOR PRODUCING SAME MTR, MRM1, MT-CO1 TLR8 2656/4885TYR 1788/4885GPR84 4439/4885
US-20150368224-A1 NOVEL ALLYL COMPOUND AND METHOD FOR PRODUCING THE SAME CBR1, CYP11B1, CYP11B2 TLR8 4513/4885TYR 1912/4885GPR84 3276/4885
US-10723690-B2 (Meth)acryloyl compound and method for producing same MTR, MRM1, MT-CO1 TLR8 2816/4885TYR 1780/4885GPR84 4528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.