Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2165693 | 0.98 | KMT2A (0.36) | KMT2AMEN1NPC1HPNHTR2C | |
| SCHEMBL2639115 | 0.79 | HTR2C (0.36) | KMT2AMEN1NPC1HPNHTR2C | |
| SCHEMBL9288607 | 0.77 | LMNA (0.41) | KMT2AMEN1HTR2CACHEHDAC4 | |
| SCHEMBL9458426 | 0.75 | OPRK1 (0.43) | KMT2AMEN1NPC1ACHEHDAC4 | |
| SCHEMBL7141443 | 0.73 | HDAC4 (0.37) | KMT2AMEN1NPC1HPNHTR2C | |
| SCHEMBL5175848 | 0.73 | TDP1 (0.33) | KMT2AMEN1NPC1HPNHTR2C | |
| SCHEMBL6151708 | 0.71 | ACHE (0.52) | KMT2AMEN1NPC1HPNHTR2C | |
| SCHEMBL4603853 | 0.68 | MEN1 (0.37) | KMT2AMEN1HTR2CHTR2AHTR2B | |
| SCHEMBL6984486 | 0.67 | KMT2A (0.34) | KMT2AMEN1HTR2CHDAC4TDP1 | |
| SCHEMBL5025393 | 0.67 | CYP2C19 (0.34) | HTR2CHDAC4TDP1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373425-A2 | PROTECTIVE ARTICLES | 3M Innovative Properties Company (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002070623-A2 | PROTECTIVE ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |