SCHEMBL6547130

SCHEMBL6547130

Cc1ccc(C(C)CCc2ccccc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.50
POLB P06746 2/20 0.48
ALDH1A1 P00352 3/20 0.46
ALOX12 P18054 3/20 0.44
GAA P10253 2/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
RECQL P46063 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546729 0.83 SIGMAR1 (0.44) GAAMEN1KMT2A
Diphenylmethane SCHEMBL10899649 0.76 CASR (0.47) POLBGAASMN1; SMN2NPC1RAB9A
SCHEMBL6546964 0.75 ALDH1A1 (0.54) NR3C1POLBALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL9688997 0.75 SRC (0.41) POLBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL15919018 0.75 SRC (0.41) ALDH1A1LMNATDP1CYP1A2
SCHEMBL20725099 0.75 TAAR1 (0.44) NR3C1SMN1; SMN2NPC1RAB9ATDP1
SCHEMBL6547126 0.75 ALOX12 (0.48) NR3C1POLBALDH1A1ALOX12GAA
SCHEMBL6546230 0.75 NR3C1 (0.43) NR3C1GAASMN1; SMN2LMNAMEN1
SCHEMBL9587636 0.74 LMNA (0.43) NR3C1POLBALDH1A1ALOX12HTT
SCHEMBL28263806 0.72 TSHR (0.42) NR3C1ALDH1A1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed