Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6550168 | 0.76 | TSHR (0.43) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1721592 | 0.76 | GAA (0.54) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL13026657 | 0.75 | TSHR (0.59) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2991047 | 0.73 | PTGS2 (0.67) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1892145 | 0.73 | TSHR (0.52) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1805007 | 0.72 | SMN1; SMN2 (0.59) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7452249 | 0.71 | CA2 (0.50) | MAPK1 | |
| SCHEMBL19181037 | 0.71 | MMP2 (0.45) | TSHRALDH1A1KMT2AMEN1PTGS2 | |
| SCHEMBL2035701 | 0.71 | TSHR (0.50) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7456723 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1PTGS2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | claimed |
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | disclosed |