Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547519 | 0.78 | GAA (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL6547816 | 0.76 | TSHR (0.46) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6548071 | 0.73 | CA2 (0.52) | ALDH1A1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL6548149 | 0.73 | ALDH1A1 (0.52) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6547655 | 0.73 | PKM (0.55) | ALDH1A1PTGS2GAA | |
| SCHEMBL6548699 | 0.73 | HTR6 (0.46) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13026657 | 0.72 | TSHR (0.59) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2991047 | 0.70 | PTGS2 (0.67) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1892145 | 0.70 | TSHR (0.52) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28993337 | 0.69 | TSHR (0.50) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | claimed |
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | disclosed |