Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456723 | 0.76 | ALDH1A1 (0.54) | CA2CA12CA9CA1MMP2 | |
| SCHEMBL1721592 | 0.76 | GAA (0.54) | CA2CA12CA9CA1MMP2 | |
| SCHEMBL12017078 | 0.76 | CA2 (0.50) | CA2PLCG1CA12CA9CA1 | |
| SCHEMBL19181037 | 0.76 | MMP2 (0.45) | CA2CA1MMP2MMP1MMP9 | |
| SCHEMBL1075415 | 0.75 | HTR6 (0.50) | CA2CA12CA9CA1MMP2 | |
| SCHEMBL31599165 | 0.74 | HTT (0.52) | CA2CA12CA9CA1MMP1 | |
| SCHEMBL6547691 | 0.71 | CA2 (0.55) | CA2F2CYP2A6HTT | |
| SCHEMBL10050325 | 0.71 | PLCG1 (0.59) | CA2PLCG1CA12CA9CA1 | |
| SCHEMBL15603477 | 0.71 | CA2 (0.45) | CA2PLCG1CA12CA9CA1 | |
| SCHEMBL6548514 | 0.71 | ALDH1A1 (0.57) | CA2CA9CA1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015035426-A1 | ANTIMICROBIAL COMPUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
| US-20100081647-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK LIMITED (GB) | 2010-04-01 | — | — | US | disclosed |
| EP-1162962-A4 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1162962-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6232503-B1 | MICROBIOCIDES | LONZA INC. | 2001-05-15 | — | — | US | disclosed |
| WO-2000056305-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081647-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | GABRA5, GABRA6, GABRA1 | CA2 869/4885PLCG1 4646/4885CA12 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.