SCHEMBL6548539

SCHEMBL6548539

CCCCNC(=O)CCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 0.61
EPHX2 P34913 4/20 0.57
NAAA Q02083 1/20 0.57
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 1/20 0.54
SLC6A5 Q9Y345 1/20 0.54
FAAH O00519 5/20 0.53
KDM4E B2RXH2 1/20 0.53
CNR1 P21554 3/20 0.51
CNR2 P34972 2/20 0.51
PLA2G2A P14555 1/20 0.50
AKR1B1 P15121 1/20 0.50
PLA2G4A P47712 1/20 0.50
HPGD P15428 1/20 0.50
DNM1 Q05193 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619697 0.94 CASP2 (0.70) CASP2EPHX2NAAAMEN1MAPT
SCHEMBL20349820 0.92 EPHX2 (0.55) CASP2EPHX2NAAAMEN1MAPT
SCHEMBL10686810 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E
SCHEMBL94472 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E
SCHEMBL10420519 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E
SCHEMBL1001785 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E
SCHEMBL10767322 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E
SCHEMBL93996 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E
SCHEMBL10422182 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E
SCHEMBL8337296 0.92 CASP2 (0.74) CASP2EPHX2NAAAFAAHKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-12123107-B2 Reversibly thermochromic composite fiber KABUSHIKI KAISHA PILOT CORPORATION (JP) 2024-10-22 US disclosed
US-20230233549-A1 METHODS OF USING 4(1H)-QUINOLONE DERIVATIVES ACADEMIA SINICA (TW) 2023-07-27 US disclosed
US-11638705-B2 4(1H)-quinolone derivatives and uses thereof ACADEMIA SINICA (TW) 2023-05-02 US disclosed
US-20220169919-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2022-06-02 US disclosed
EP-3950068-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME THE PILOT INK CO., LTD. (JP) 2022-02-09 EP disclosed
US-20210355608-A1 REVERSIBLY THERMOCHROMIC COMPOSITE FIBER THE PILOT INK CO., LTD. (JP) 2021-11-18 US disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-6407064-B2 A MORPHOLINO RING CONTAINING ALKYLAMINOALCOHOL DERIVATIVE OR SALTS USEFUL FOR TREATING NEURONAL DISEASES AND AN AGENT FOR PROTECTING BRAIN SEIKAGAKU CORPORATION (JP) 2002-06-18 US disclosed
EP-0873881-B1 Reversible thermochromic compositions PILOT INK CO LTD (JP) 2001-10-17 EP disclosed
US-20010003741-A1 Aminoalcohol derivative and medicament comprising the same SEIKAGAKU CORPORATION (JP) 2001-06-14 US disclosed
EP-1106609-A2 Aminoalcohol derivative and medicament comprising the same SEIKAGAKU CORPORATION (JP) 2001-06-13 EP disclosed
US-5919404-A MIXTURE OF COLOR DEVELOPING COMPOUND AND ELECTRON ACCEPTORALKOXYPHENOL COMPOUND THE PILOT INK CO., LTD. (JP) 1999-07-06 US disclosed
EP-0873881-A1 Reversible thermochromic compositions The Pilot Ink CO., Ltd. (JP) 1998-10-28 EP disclosed
US-4654356-A BRONCHODILATORS, ANTIASTHMA, THROMBOSIS ANTICOAGULANTS E. R. SQUIBB & SONS, INC. (US) 1987-03-31 US disclosed
US-4647573-A 7-oxabicycloheptane substituted thioamide-amide prostaglandin analogs E. R. SQUIBB & SONS, INC. (US) 1987-03-03 US disclosed
EP-0210664-A2 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs E.R. Squibb & Sons, Inc. (US) 1987-02-04 EP disclosed
US-4302573-A Metal salt/amine complexes as epoxy resin catalytic curing agents CIBA-GEIGY CORPORATION (US) 1981-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638705-B2 4(1H)-quinolone derivatives and uses thereof TUBB1, TUBB3, TUBB CASP2 584/4885EPHX2 4648/4885NAAA 4626/4885
US-20010003741-A1 Aminoalcohol derivative and medicament comprising the same SGMS2, FABP7, SGMS1 CASP2 65/4885EPHX2 1604/4885NAAA 186/4885
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB CASP2 1862/4885EPHX2 2279/4885NAAA 4573/4885
US-20230233549-A1 METHODS OF USING 4(1H)-QUINOLONE DERIVATIVES TUBB1, TUBB3, TUBB CASP2 507/4885EPHX2 4572/4885NAAA 4651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.