Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.74 |
| ▸ | NAAA | Q02083 | 1/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.68 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94472 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL8337296 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL10420519 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL8356691 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL1001785 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL10422182 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL10686810 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL10767322 | 1.00 | CASP2 (0.74) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL30678823 | 0.98 | CASP2 (0.71) | CASP2NAAAEPHX2PLA2G2AFAAH | |
| SCHEMBL30835571 | 0.98 | CASP2 (0.71) | CASP2NAAAEPHX2PLA2G2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468996-B1 | ANTI-EGFR ANTIBODY DRUG CONJUGATES | ABBVIE INC (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20180344859-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | ALUMEND, LLC (US) | 2018-12-06 | — | — | US | disclosed |
| US-20180344858-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | ALUMEND, LLC (US) | 2018-12-06 | — | — | US | disclosed |
| US-9884121-B2 | Biomaterials and a method for making and using same | ALUMEND, LLC (US) | 2018-02-06 | — | — | US | disclosed |
| US-9855337-B2 | Biomaterials and a method for making and using the same | ALUMEND, LLC (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160175449-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | ALUMEND, LLC (US) | 2016-06-23 | — | — | US | disclosed |
| US-20140128352-A1 | COMPOUNDS AND METHODS FOR MODULATING MITOCHONDRIAL METABOLISM AND REACTIVE OXYGEN SPECIES PRODUCTION | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2014-05-08 | — | — | US | disclosed |
| EP-2114370-B1 | NOVEL BIOMATERIALS FOR OCULAR DRUG DELIVERY AND A METHOD FOR MAKING AND USING SAME | ALLERGAN INC (US) | 2012-10-03 | — | — | EP | disclosed |
| US-8252771-B2 | A modified chitosan and a prostaglandin, prostamide, non-steroidal anti-inflammatory drug, or a corticosteroid; opthalmic drug delivery solution; improved bioavailability | ALLERGAN, INC. (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2425816-A2 | A pharmaceutical composition for use in treating an ocular disease or condition and a method for producing the composition | Allergan, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |
| EP-2114370-A2 | NOVEL BIOMATERIALS FOR OCULAR DRUG DELIVERY AND A METHOD FOR MAKING AND USING SAME | Allergan, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| US-7442558-B2 | Phthalamide-lanthanide complexes for use as luminescent markers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |
| US-20080207561-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | ALLERGAN, INC. | 2008-08-28 | — | — | US | disclosed |
| US-20080200948-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | PHOTOBIOMED CORPORATION (US) | 2008-08-21 | — | — | US | disclosed |
| WO-2008094659-A2 | NOVEL BIOMATERIALS FOR OCULAR DRUG DELIVERY AND A METHOD FOR MAKING AND USING SAME | ALLERGAN, INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008094675-A2 | NOVEL BIOMATERIALS AND METHODS FOR MAKING AND USING SAME | PHOTOBIOMED CORPORATION (US) | 2008-08-07 | — | — | WO | disclosed |
| US-4921942-A | Organometallic compounds | STEPAN COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4724174-A | AMIDO CARBOXYL SOAPS; FILM-FORMING; SUBSTANTIVITY | STEPAN COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4675422-A | ALUMINUM COATINGS | STEPAN COMPANY (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0220934-A2 | Aluminium carboxylates | STEPAN COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200948-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | MMP1, PLOD3, MMP2 | CASP2 3112/4885NAAA 388/4885EPHX2 428/4885 |
| US-20140128352-A1 | COMPOUNDS AND METHODS FOR MODULATING MITOCHONDRIAL METABOLISM AND REACTIVE OXYGEN SPECIES PRODUCTION | PC, PCK2, TXNRD2 | CASP2 963/4885NAAA 2022/4885EPHX2 3509/4885 |
| US-20180344859-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | MMP1, PLOD3, MMP2 | CASP2 3112/4885NAAA 388/4885EPHX2 428/4885 |
| US-20180344858-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | MMP1, PLOD3, MMP2 | CASP2 3112/4885NAAA 388/4885EPHX2 428/4885 |
| US-20160175449-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | MMP1, PLOD3, MMP2 | CASP2 3112/4885NAAA 388/4885EPHX2 428/4885 |
| US-20080207561-A1 | NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME | PTGES, PTGES2, PTGIS | CASP2 1230/4885NAAA 809/4885EPHX2 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.