Quinoline

Quinoline

SCHEMBL655206

B.c1ccc2ncccc2c1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.94
CYP3A4 P08684 2/20 0.60
NPC1 O15118 2/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
MAPT P10636 4/20 0.53
KDM4E B2RXH2 4/20 0.52
HTT P42858 3/20 0.52
CASP1 P29466 2/20 0.52
TP53 P04637 2/20 0.52
HSP90AA1 P07900 2/20 0.52
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 1/20 0.52
CASP7 P55210 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
NR4A2 P43354 1/20 0.52
HSP90AB1 P08238 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28162459 0.97 ALDH1A1 (0.90) ALDH1A1CYP3A4NPC1POLBRAB9A
Phenazine SCHEMBL12804247 0.97 ALDH1A1 (0.90) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL2774 0.97 ALDH1A1 (1.00) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL29349552 0.97 ALDH1A1 (1.00) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL32661377 0.97 ALDH1A1 (1.00) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL1270969 0.97 ALDH1A1 (1.00) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL29822171 0.97 ALDH1A1 (1.00) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL23202414 0.94 ALDH1A1 (0.94) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL5422407 0.94 ALDH1A1 (0.94) ALDH1A1CYP3A4NPC1POLBRAB9A
Quinoline SCHEMBL4955314 0.94 ALDH1A1 (0.94) ALDH1A1CYP3A4NPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111072695-A Organic small molecular material containing boron-containing azanaphthalene and preparation method and application thereof 华南协同创新研究院 2020-04-28 CN claimed
CN-110003256-A A kind of fused ring compound and its synthetic method and application 南京邮电大学 2019-07-12 CN claimed
US-20180346490-A1 N, C-CHELATE FOUR-COORDINATE ORGANOBORONS WITH FULL COLOURTUNABILITY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-12-06 US claimed
CN-106317383-A Organic monomer containing 8-hydroxyquinoline boron, conjugated polymer based on monomer, preparation method and application 陕西师范大学 2017-01-11 CN claimed
WO-2016207910-A1 N, C-CHELATE FOUR-COORDINATE ORGANOBORONS WITH FULL COLOURTUNABILITY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-12-29 WO claimed
CN-104098597-B A kind of method of synthesis 4a, 8a-boron azepine naphthalene and its derivative 同济大学 2016-08-24 CN claimed
CN-121181592-B 2-Alkyl boric acid pinacol ester-2, 1-borazine naphthalene compound and preparation method thereof 江苏海洋大学 2026-03-03 CN disclosed
CN-120398937-B 2-Phenyl-4-pinacol boron-2, 1-borazine, 2-phenyl-4-pyrimidinyl-2, 1-borazine compound and preparation method thereof 江苏海洋大学 2026-02-17 CN disclosed
CN-121181592-A 2-Alkyl boric acid pinacol ester-2, 1-borazine naphthalene compound and preparation method thereof 江苏海洋大学 2025-12-23 CN disclosed
CN-120398937-A 2-Phenyl-4-pinacol boron-2, 1-borazine, 2-phenyl-4-pyrimidinyl-2, 1-borazine compound and preparation method thereof 江苏海洋大学 2025-08-01 CN disclosed
US-11957020-B2 Light-emitting device, display and color conversion substrate TORAY INDUSTRIES, INC. (JP) 2024-04-09 US disclosed
EP-3745168-B1 LIGHT-EMITTING ELEMENT, DISPLAY, AND COLOR CONVERSION SUBSTRATE TORAY INDUSTRIES (JP) 2022-08-31 EP disclosed
US-20210134890-A1 LIGHT-EMITTING DEVICE, DISPLAY AND COLOR CONVERSION SUBSTRATE TORAY INDUSTRIES, INC. (JP) 2021-05-06 US disclosed
CN-102421782-A Process for producing tetrahydropyran compound and intermediate thereof NISSAN CHEMICAL IND LTD 2012-04-18 CN disclosed
US-20120046476-A1 METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-23 US disclosed
EP-2420504-A1 METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
EP-1765358-B1 TREATMENT OR PREVENTION OF SKIN CONDITIONS OR TISSUE CONDITIONS IN ANIMALS USING BORYLOXYPYRIDYLMETHANONES ANACOR PHARMACEUTICALS INC (US) 2011-02-23 EP disclosed
CN-101389667-A Surface-modified polymerization catalysts for the preparation of low-gel polyolefin films BOREALIS TECH OY (FI) 2009-03-18 CN disclosed
CN-1071995-C Diaryl (pyridinio and isoquinolinio) boron fungicidal agents AMERICAN CYANAMID CO (US) 2001-10-03 CN disclosed
CN-1099557-A Diaryl (pyridinio and isoquinolinio) boron fungicidal agents AMERICAN CYANAMID CO (US) 1995-03-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180346490-A1 N, C-CHELATE FOUR-COORDINATE ORGANOBORONS WITH FULL COLOURTUNABILITY CNOT7, CDYL, CRY1 ALDH1A1 3195/4885CYP3A4 262/4885NPC1 458/4885
US-20210134890-A1 LIGHT-EMITTING DEVICE, DISPLAY AND COLOR CONVERSION SUBSTRATE CRY1, CYBA, CRY2 ALDH1A1 34/4885CYP3A4 12/4885NPC1 4849/4885
US-20120046476-A1 METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF HPD, CYP3A5, CYP2E1 ALDH1A1 325/4885CYP3A4 14/4885NPC1 3988/4885
US-11957020-B2 Light-emitting device, display and color conversion substrate CRY1, CYBA, CRY2 ALDH1A1 34/4885CYP3A4 12/4885NPC1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.