Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.56 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.56 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.56 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737718 | 0.93 | NPC1 (0.72) | NPC1GAARAB9ATAAR1KMT2A | |
| SCHEMBL3404533 | 0.83 | ALDH1A1 (0.62) | NPC1GAARAB9ATAAR1MAPT | |
| SCHEMBL10924887 | 0.82 | GLA (0.70) | NPC1GAARAB9ATAAR1KMT2A | |
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.82 | LMNA (0.73) | NPC1GAARAB9ATAAR1KMT2A | |
| SCHEMBL10924997 | 0.81 | KMT2A (0.68) | NPC1GAARAB9ATAAR1KMT2A | |
| SCHEMBL20029318 | 0.80 | PLAAT3 (0.68) | NPC1GAARAB9ATAAR1KMT2A | |
| SCHEMBL28982954 | 0.80 | RAB9A (0.58) | NPC1GAARAB9ATAAR1L3MBTL1 | |
| SCHEMBL11561410 | 0.79 | NPC1 (0.65) | NPC1RAB9AKMT2AMAPTL3MBTL1 | |
| SCHEMBL27783096 | 0.79 | NPC1 (0.65) | NPC1RAB9AKMT2AMAPTL3MBTL1 | |
| SCHEMBL6554125 | 0.79 | LMNA (0.65) | GAAPLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |