SCHEMBL6553063

SCHEMBL6553063

CC(=O)Oc1ccc(S(=O)(=O)c2ccc(C[C@@H](C)N)cc2)cc1C

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.47
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
TAAR1 Q96RJ0 3/20 0.38
SLC6A2 P23975 1/20 0.38
CFD P00746 1/20 0.37
SLC6A4 P31645 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6553061 0.88 KMT2A (0.38) KMT2APOLBMAPTPKMTAAR1
SCHEMBL6553968 0.87 CYP4F2 (0.42) KMT2APOLBMAPTPKMTAAR1
SCHEMBL6554093 0.87 PNMT (0.43) KMT2APOLBMAPTPKMTAAR1
SCHEMBL6540961 0.83 APEX1 (0.49) KDM4E
SCHEMBL6552730 0.82 POLB (0.66) KMT2APOLBMAPTPKMTAAR1
SCHEMBL6554516 0.81 POLB (0.50) KMT2APOLBMAPTPKMTAAR1
SCHEMBL6553983 0.80 KMT2A (0.43) KMT2APOLBMAPTPKM
SCHEMBL6553965 0.78 NAMPT (0.37) KMT2ATAAR1SLC6A2
SCHEMBL6554091 0.78 PNMT (0.39) PKMTAAR1SLC6A2
SCHEMBL9660880 0.77 KMT2A (0.57) KMT2APOLBMAPTPKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1389185-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-02-18 EP disclosed
WO-2002094770-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-28 WO disclosed