Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6554982 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL6554859 | 0.86 | HTR7 (0.33) | KDM4EALDH1A1CYP2A6HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL6892837 | 0.84 | KDM4E (0.36) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL388936 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL7933297 | 0.81 | MEN1 (0.38) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL5068152 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL8635888 | 0.79 | KDM4E (0.34) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL673327 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Fluoride Ion SCHEMBL7641950 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1CYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL8633679 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1CYP2A6CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773237-B1 | Olefin polymerization catalyst system | MITSUI CHEMICALS INC (JP) | 2004-02-18 | — | — | EP | disclosed |