Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217024 | 0.90 | CES2 (0.61) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL29589535 | 0.87 | CES2 (0.67) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL9369669 | 0.86 | CA1 (0.59) | ALDH1A1CYP1A2CA1CA2CES2 | |
| 1,4-Dimethoxybenzene SCHEMBL27728351 | 0.86 | LDHA (0.59) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL391885 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL9614771 | 0.83 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL18082660 | 0.83 | PLK1 (0.56) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL28883199 | 0.82 | ALDH1A1 (0.66) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL12453 | 0.82 | CES2 (0.61) | ALDH1A1CYP1A2CA1CA2CES2 | |
| SCHEMBL6981600 | 0.81 | PARP10 (0.55) | ALDH1A1PARP10MAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627670-B | Aryl alkyl acid-cyclophosphamide derivative as well as preparation method and application thereof | UNIV SHIJIAZHUANG | 2014-11-26 | — | — | CN | claimed |
| CN-102070438-A | Preparation method of gamma-p-methoxyphenyl butyrate | TIANJIN YIHENG TECHNOLOGY DEV CO LTD | 2011-05-25 | — | — | CN | claimed |
| CN-102060692-A | Preparation method of gamma-(p-methoxyphenyl) butyric acid | HUNAN TIANCHENG PHARMACEUTICAL COMPANY LTD | 2011-05-18 | — | — | CN | claimed |
| CN-102627670-B | Aryl alkyl acid-cyclophosphamide derivative as well as preparation method and application thereof | UNIV SHIJIAZHUANG | 2014-11-26 | — | — | CN | disclosed |
| CN-102627670-A | Aryl alkyl acid-cyclophosphamide derivative as well as preparation method and application thereof | UNIV SHIJIAZHUANG | 2012-08-08 | — | — | CN | disclosed |
| CN-102070438-A | Preparation method of gamma-p-methoxyphenyl butyrate | TIANJIN YIHENG TECHNOLOGY DEV CO LTD | 2011-05-25 | — | — | CN | disclosed |
| CN-102060685-A | Synthesis method of 2,4,5-trimethoxy-alpha-halogenated acetophenone | HUNAN TIANCHENG PHARMACEUTICAL COMPANY LTD | 2011-05-18 | — | — | CN | disclosed |
| CN-102060692-A | Preparation method of gamma-(p-methoxyphenyl) butyric acid | HUNAN TIANCHENG PHARMACEUTICAL COMPANY LTD | 2011-05-18 | — | — | CN | disclosed |
| EP-1016653-B1 | Preparation of high-dye yield couplers and intermediates useful therein | EASTMAN KODAK CO (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6602895-B2 | Inhibitors of factor Xa with a neutral P1 specificity group | BRISTOL-MYERS SQUIBB COMPANY | 2003-08-05 | — | — | US | disclosed |
| US-20030092740-A1 | Inhibitors of factor Xa with a neutral P1 specificity group | GALEMMO ROBERT A (US) | 2003-05-15 | — | — | US | disclosed |
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |
| WO-1998057937-A2 | INHIBITORS OF FACTOR XA WITH A NEUTRAL P1 SPECIFICITY GROUP | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-23 | — | — | WO | disclosed |
| EP-0746544-B1 | NOVEL INDOLE DERIVATIVES USEFUL TO TREAT ESTROGEN-RELATED NEOPLASMS AND DISORDERS | MERRELL PHARMA INC (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0746544-A1 | NOVEL INDOLE DERIVATIVES USEFUL TO TREAT ESTROGEN-RELATED NEOPLASMS AND DISORDERS | MERRELL PHARMACEUTICALS INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022524-A1 | NOVEL INDOLE DERIVATIVES USEFUL TO TREAT ESTROGEN-RELATED NEOPLASMS AND DISORDERS | MERRELL PHARMACEUTICALS INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| EP-0412933-B1 | Coating compositions | CIBA GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |
| US-5183842-A | Mixture of ketoacid and amine with film-forming binder, curing | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| US-5128396-A | Corrosion inhibiting primers on metallic substrates | CIBA-GEIGY CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0412933-A1 | Coating compositions | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092740-A1 | Inhibitors of factor Xa with a neutral P1 specificity group | F12, F11, SERPINC1 | ALDH1A1 1329/4885CYP1A2 995/4885CA1 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.