Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557586 | 0.91 | KDM4E (0.52) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6555842 | 0.91 | TSHR (0.52) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6557988 | 0.90 | L3MBTL1 (0.51) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6557322 | 0.88 | KDM4E (0.52) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6557964 | 0.87 | ACKR3 (0.52) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6557887 | 0.81 | HTR7 (0.51) | HSD17B10USP2RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6555790 | 0.78 | MEN1 (0.52) | HSD17B10USP2RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5345373 | 0.78 | HTR1A (0.51) | L3MBTL1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL6555584 | 0.78 | PDE4A (0.50) | KDM4ETSHRHSD17B10USP2RAB9A | |
| SCHEMBL6555779 | 0.78 | TNF (0.42) | L3MBTL1KDM4EALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | disclosed |