Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555842 | 0.86 | TSHR (0.52) | HIF1AHSD17B10RAB9AUSP2ALDH1A1 | |
| SCHEMBL6557887 | 0.85 | HTR7 (0.51) | HIF1AHSD17B10RAB9AUSP2ALDH1A1 | |
| SCHEMBL6557586 | 0.84 | KDM4E (0.52) | HIF1AHSD17B10RAB9AUSP2ALDH1A1 | |
| SCHEMBL6555851 | 0.82 | MAPT (0.47) | HIF1AMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL6555790 | 0.81 | MEN1 (0.52) | HIF1AHSD17B10RAB9AUSP2ALDH1A1 | |
| SCHEMBL6557412 | 0.80 | PDE10A (0.57) | USP2ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6557988 | 0.80 | L3MBTL1 (0.51) | HSD17B10MAPTRAB9AUSP2ALDH1A1 | |
| SCHEMBL7636675 | 0.79 | MRGPRX4 (0.57) | MAPTRAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6555761 | 0.79 | EIF4EBP1 (0.52) | MAPTALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL6557990 | 0.79 | ACHE (0.45) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | disclosed |