Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557887 | 0.94 | HTR7 (0.51) | MEN1KMT2ASMN1; SMN2BLMPDE10A | |
| SCHEMBL6557412 | 0.91 | PDE10A (0.57) | MEN1KMT2APDE10AHTR7CYP1A2 | |
| SCHEMBL6557990 | 0.86 | ACHE (0.45) | PDE10AHSD17B10HTR7ACHE | |
| SCHEMBL6555842 | 0.85 | TSHR (0.52) | SMN1; SMN2HSD17B10LMNAHTR7ALDH1A1 | |
| SCHEMBL6555584 | 0.81 | PDE4A (0.50) | MEN1KMT2ASMN1; SMN2HSD17B10LMNA | |
| SCHEMBL6557586 | 0.79 | KDM4E (0.52) | SMN1; SMN2PDE10AHSD17B10ALDH1A1HIF1A | |
| SCHEMBL6557988 | 0.78 | L3MBTL1 (0.51) | KMT2ASMN1; SMN2HSD17B10ALDH1A1USP2 | |
| SCHEMBL6556016 | 0.78 | L3MBTL1 (0.51) | SMN1; SMN2PDE10AHSD17B10ALDH1A1USP2 | |
| SCHEMBL6557322 | 0.77 | KDM4E (0.52) | KMT2ASMN1; SMN2PDE10AHSD17B10ALDH1A1 | |
| SCHEMBL6555851 | 0.77 | MAPT (0.47) | LMNAMAPK1HTR7CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | claimed |