S-Trityl-L-Cysteine

S-Trityl-L-Cysteine

SCHEMBL655694

N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O.[LiH]

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.82
DNMT1 P26358 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
S-Trityl-L-Cysteine SCHEMBL655692 1.00 KIF11 (0.82) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL6891349 0.98 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768203 0.98 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768202 0.98 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL11190175 0.97 KIF11 (0.82) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL11190178 0.97 KIF11 (0.82) KIF11DNMT1
SCHEMBL12851543 0.89 KIF11 (1.00) KIF11DNMT1
SCHEMBL14537506 0.88 KIF11 (1.00) KIF11DNMT1
SCHEMBL7753308 0.86 KIF11 (0.68) KIF11DNMT1
SCHEMBL2838308 0.86 KIF11 (0.68) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2837384-A1 Glutathione based delivery system Industrial Technology Research Institute (TW) 2015-02-18 EP disclosed
EP-1891962-B1 Glutathione based delivery system IND TECH RES INST (TW) 2014-08-13 EP disclosed
US-8673863-B2 Glutathione-based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-03-18 US disclosed
US-8569239-B2 Glutathione based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-10-29 US disclosed
US-20120046445-A1 GLUTATHIONE-BASED DELIVERY SYSTEM WANG AE-JUNE (TW) 2012-02-23 US disclosed
US-8067380-B2 Glutathione-based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-11-29 US disclosed
US-20100166849-A1 GLUTATHIONE BASED DELIVERY SYSTEM WANG AE-JUNE 2010-07-01 US disclosed
US-7704956-B2 Glutathione-based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-04-27 US disclosed
US-7700564-B2 Glutathione based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-04-20 US disclosed
US-20090123531-A1 GLUTATHIONE-BASED DELIVERY SYSTEM INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-05-14 US disclosed
US-20090060991-A1 GLUTATHIONE BASED DELIVERY SYSTEM WANG AE-JUNE 2009-03-05 US disclosed
US-7446096-B2 Glutathione based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2008-11-04 US disclosed
US-20080095836-A1 Glutathione-based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-04-24 US disclosed
EP-1891962-A1 Glutathione based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2008-02-27 EP disclosed
US-20070141133-A1 Liposomes; analgesics; glutathione is covalently bound to polyethylene glycol,wherein the polyethylene glycol is covalently bound to vitamin E or a phospholipid INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046445-A1 GLUTATHIONE-BASED DELIVERY SYSTEM GSTO1, GPX4, GPX1 KIF11 3642/4885DNMT1 2649/4885
US-20100166849-A1 GLUTATHIONE BASED DELIVERY SYSTEM GPX4, GSTO1, GPX1 KIF11 3612/4885DNMT1 2551/4885
US-20070141133-A1 Liposomes; analgesics; glutathione is covalently bound to polyethylene glycol,wherein the polyethylene glycol is covalently bound to vitamin E or a phospholipid GSTO1, GSTP1, GSTA1 KIF11 3404/4885DNMT1 2415/4885
US-20080095836-A1 Glutathione-based delivery system GSTP1, GSS, GSTA1 KIF11 3532/4885DNMT1 3858/4885
US-20090060991-A1 GLUTATHIONE BASED DELIVERY SYSTEM GPX4, GSTO1, GPX1 KIF11 3612/4885DNMT1 2551/4885
US-20090123531-A1 GLUTATHIONE-BASED DELIVERY SYSTEM GSTO1, GPX4, GPX1 KIF11 3642/4885DNMT1 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.