SCHEMBL2838308

SCHEMBL2838308

NC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.68
DNMT1 P26358 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753308 1.00 KIF11 (0.68) KIF11DNMT1
SCHEMBL15978681 1.00 KIF11 (0.68) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768202 0.88 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768203 0.88 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL6891349 0.88 KIF11 (0.85) KIF11DNMT1
SCHEMBL14432855 0.87 KIF11 (0.83) KIF11DNMT1
SCHEMBL15848662 0.87 KIF11 (0.64) KIF11DNMT1
SCHEMBL14432853 0.87 KIF11 (0.83) KIF11DNMT1
SCHEMBL27988674 0.87 KIF11 (0.65) KIF11DNMT1
SCHEMBL27988671 0.87 KIF11 (0.65) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606233-A Preparation method of S-trityl-L-cysteamine 康化(上海)新药研发有限公司 2023-08-18 CN claimed
US-12565506-B2 Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals Clarity Pharmaceuticals Ltd (AU) 2026-03-03 US disclosed
US-12503498-B2 Fc containing polypeptides with altered glycosylation and reduced effector function GENZYME CORPORATION (US) 2025-12-23 US disclosed
EP-4640239-A2 SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES Genzyme Corporation (US) 2025-10-29 EP disclosed
EP-4015535-B1 SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES GENZYME CORP (US) 2025-08-06 EP disclosed
CN-119552215-A Tumor targeting polypeptides, conjugates comprising same, compositions and uses 苏州星洲生物科技有限公司 2025-03-04 CN disclosed
US-20250066497-A1 SITE-SPECIFIC ANTIBODY-DRUG CONJUGATION THROUGH GLYCOENGINEERING GENZYME CORPORATION 2025-02-27 US disclosed
WO-2025006830-A2 COMPOUNDS FOR THE TREATMENT OF RETINITIS PIGMENTOSA AND METHODS OF MAKING AND USING THE SAME UNIVERSITY OF MISSISSIPPI (US) 2025-01-02 WO disclosed
CN-113975406-B Glycoengineered antibody drug conjugates 建新公司 2024-11-22 CN disclosed
US-12110338-B2 Site-specific antibody-drug conjugation through glycoengineering GENZYME CORPORATION (US) 2024-10-08 US disclosed
US-20040029814-A1 Dipeptide nitriles ALTMANN EVA (CH) 2004-02-12 US disclosed
US-6353017-B1 INHIBITORS OF CATHESPINS USING DIPEPTIDE NITRILES AS ANTIINFLAMMATORY AGENTS AND ANTIARTHRITIC AGENTS NOVARTIS AG (CH) 2002-03-05 US disclosed
US-6313123-B1 FOR THERAPY OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, SEPSIS, AIDS, ULCERATIVE COLITIS, MULTIPLE SCLEROSIS, CROHN'S DISEASE AND DEGENERATIVE CARTILAGE LOSS AMERICAN CYANAMID COMPANY 2001-11-06 US disclosed
EP-1149074-A1 ACETYLENIC SULFONAMIDE THIOL TACE INHIBITORS American Cyanamid Company (US) 2001-10-31 EP disclosed
EP-0633267-B1 Process for the preparation of alpha-amino acid amide for use in peptide synthesis SOLVAY (BE) 2001-09-26 EP disclosed
EP-1068176-A1 CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS Jomaa, Hassan (DE) 2001-01-17 EP disclosed
WO-2000044716-A1 ACETYLENIC SULFONAMIDE THIOL TACE INHIBITORS AMERICAN CYANAMID COMPANY (US) 2000-08-03 WO disclosed
WO-2000027803-A1 CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS JOMAA, HASSAN (DE) 2000-05-18 WO disclosed
US-5506362-A Process for the preparation of an α-amino acid amide SOLVAY (SOCIETE ANONYME) (BE) 1996-04-09 US disclosed
EP-0633267-A1 Process for the preparation of an alpha-amino acid amide for use in peptide synthesis SOLVAY (Société Anonyme) (BE) 1995-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565506-B2 Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals CA12, CLTC, CA13 KIF11 3449/4885DNMT1 4238/4885
US-12110338-B2 Site-specific antibody-drug conjugation through glycoengineering CD2BP2, SIGLEC7, B3GAT3 KIF11 2605/4885DNMT1 1142/4885
US-20250066497-A1 SITE-SPECIFIC ANTIBODY-DRUG CONJUGATION THROUGH GLYCOENGINEERING SIGLEC9, SIGLEC7, STT3B KIF11 2232/4885DNMT1 551/4885
US-12503498-B2 Fc containing polypeptides with altered glycosylation and reduced effector function FCGR3B, FCGRT, FCGR2A KIF11 4467/4885DNMT1 2293/4885
US-20040029814-A1 Dipeptide nitriles NOS1, CTSL, CTSS KIF11 4552/4885DNMT1 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.