Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | CBR1 | P16152 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558343 | 0.82 | NPC1 (0.41) | GAANPC1RAB9ATP53HSD17B10 | |
| SCHEMBL6559436 | 0.80 | MAPK1 (0.32) | GAAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL6558372 | 0.80 | POLB (0.43) | TP53HSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL6557418 | 0.79 | HSD17B10 (0.36) | GAAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL6559547 | 0.77 | MEN1 (0.34) | GAAHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL6065016 | 0.70 | KMT2A (0.33) | RAB9AP2RX7KMT2AMEN1MAPT | |
| SCHEMBL6065740 | 0.70 | F2 (0.41) | GAANPC1RAB9ATP53HSD17B10 | |
| SCHEMBL6065131 | 0.69 | LMNA (0.40) | GAARAB9AALDH1A1HPGDCYP2C19 | |
| SCHEMBL6557082 | 0.69 | PRMT5 (0.40) | HSD17B10KMT2AMEN1CYP1A2 | |
| SCHEMBL6066190 | 0.69 | SMN1; SMN2 (0.35) | NPC1RAB9AARKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |