SCHEMBL655717

SCHEMBL655717

CC(=O)OCC=COC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.35
NAAA Q02083 2/20 0.33
CYP19A1 P11511 1/20 0.32
ALDH1A1 P00352 4/20 0.32
HTT P42858 1/20 0.32
ALOX15 P16050 1/20 0.32
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4996746 0.75 CACNA1B (0.40) EPHX1ALDH1A1ALOX15LMNAHSD17B10
SCHEMBL9998013 0.75 CACNA1B (0.40) EPHX1ALDH1A1ALOX15LMNAHSD17B10
SCHEMBL6988173 0.74 LMNA (0.35) EPHX1ALDH1A1ALOX15LMNAHSD17B10
SCHEMBL10438900 0.71 ALDH1A1 (0.35) EPHX1ALDH1A1ALOX15LMNAHSD17B10
SCHEMBL11070169 0.70 HTT (0.42) EPHX1NAAAHTTALOX15LMNA
SCHEMBL74779 0.70 ALDH1A1 (0.50) ALDH1A1ALOX15LMNAHSD17B10
SCHEMBL221749 0.70 ALDH1A1 (0.50) ALDH1A1ALOX15LMNAHSD17B10
SCHEMBL271027 0.70 ALDH1A1 (0.50) ALDH1A1ALOX15LMNAHSD17B10
SCHEMBL2470876 0.69
SCHEMBL15748576 0.69 NAAA (0.42) EPHX1NAAACYP19A1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070020210-A1 Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents MONELL CHEMICAL SENSES CENTER 2007-01-25 US claimed
CN-118697922-A Perfume dispersing device 弗门尼舍有限公司 2024-09-27 CN disclosed
CN-115651762-A Alcohol with floral scent 弗门尼舍有限公司 2023-01-31 CN disclosed
CN-105873963-B Polymer compositions comprising and releasing odorous active compounds 阿肯马法国公司 2021-10-01 CN disclosed
CN-106367212-B Liquid softener composition 狮王株式会社 2021-04-20 CN disclosed
CN-105916970-B Powdery musk odorant macrocycles 弗门尼舍有限公司 2019-12-10 CN disclosed
CN-108136063-A Perfume dispersing device 弗门尼舍有限公司 2018-06-08 CN disclosed
EP-3066138-A1 POLYMERIC COMPOSITION COMPRISING AND RELEASING AN ODORIFEROUS ACTIVE COMPOUND Arkema France (FR) 2016-09-14 EP disclosed
WO-2015067722-A1 POLYMERIC COMPOSITION COMPRISING AND RELEASING AN ODORIFEROUS ACTIVE COMPOUND ARKEMA FRANCE (FR) 2015-05-14 WO disclosed
US-20120077722-A1 AMBERGRIS FRAGRANCE SYMRISE AG (DE) 2012-03-29 US disclosed
US-8119587-B2 Microcapsules GIVAUDAN SA (CH) 2012-02-21 US disclosed
EP-2111214-B1 MICROCAPSULES GIVAUDAN SA (CH) 2011-04-13 EP disclosed
US-20080131389-A1 Hair Relaxer SHOWA DENKO K.K. (JP) 2008-06-05 US disclosed
EP-1845940-A1 HAIR RELAXER Showa Denko K.K. (JP) 2007-10-24 EP disclosed
WO-2006083031-A1 HAIR RELAXER SHOWA DENKO K.K. (JP) 2006-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120077722-A1 AMBERGRIS FRAGRANCE TRPA1, TAS2R31, TAS2R1 EPHX1 955/4885NAAA 521/4885CYP19A1 500/4885
US-20080131389-A1 Hair Relaxer BHMT2, BHMT, MGMT EPHX1 2817/4885NAAA 411/4885CYP19A1 2443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.