Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6066190 | 0.83 | SMN1; SMN2 (0.35) | MAPTKDM4ERAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6065131 | 0.81 | LMNA (0.40) | ALDH1A1KDM4ERAB9AGAASMN1; SMN2 | |
| SCHEMBL6065097 | 0.79 | PKM (0.45) | F2ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL6065953 | 0.77 | F2 (0.46) | F2F12ALDH1A1MAPTKDM4E | |
| SCHEMBL6065771 | 0.75 | LMNA (0.35) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL6065016 | 0.74 | KMT2A (0.33) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20064247 | 0.72 | ALDH1A1 (0.43) | F2F12ALDH1A1MAPTKDM4E | |
| SCHEMBL6557414 | 0.70 | MTNR1A (0.40) | ALDH1A1MAPTRAB9AHSD17B10CYP1A2 | |
| SCHEMBL6558343 | 0.69 | NPC1 (0.41) | ALDH1A1MAPTKDM4ERAB9AHSD17B10 | |
| SCHEMBL6557067 | 0.69 | P2RX3 (0.35) | ALDH1A1MAPTKDM4ERAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |