Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558943 | 0.96 | KIF11 (0.37) | KIF11HRH4HRH3MAOA | |
| SCHEMBL6557087 | 0.75 | SIGMAR1 (0.42) | — | |
| SCHEMBL6557081 | 0.74 | NPSR1 (0.43) | — | |
| SCHEMBL13835480 | 0.71 | TRPA1 (0.35) | SCN4AKCNN4 | |
| SCHEMBL5147620 | 0.70 | KIF11 (0.36) | KIF11KCNN4 | |
| SCHEMBL31518957 | 0.69 | PLK4 (0.41) | — | |
| SCHEMBL8973702 | 0.67 | KIF11 (0.41) | KIF11MAOAKCNN4 | |
| SCHEMBL1319238 | 0.63 | AKT2 (0.45) | HRH4HRH3AKT2 | |
| SCHEMBL6558942 | 0.63 | KCNN4 (0.39) | KIF11KCNN4 | |
| Hydrochloric Acid SCHEMBL6558352 | 0.62 | HRH3 (0.40) | HRH4HRH3CYP2A6AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |