Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 10/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558387 | 0.96 | KIF11 (0.38) | KIF11MAOAHRH3HRH4 | |
| SCHEMBL6557081 | 0.75 | NPSR1 (0.43) | — | |
| SCHEMBL6557087 | 0.74 | SIGMAR1 (0.42) | — | |
| SCHEMBL13835480 | 0.70 | TRPA1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6558967 | 0.68 | HRH3 (0.43) | HRH3HRH4HRH1HRH2 | |
| SCHEMBL31518957 | 0.68 | PLK4 (0.41) | — | |
| SCHEMBL5147620 | 0.67 | KIF11 (0.36) | KIF11 | |
| SCHEMBL8973702 | 0.63 | KIF11 (0.41) | KIF11MAOAHRH1 | |
| SCHEMBL2283152 | 0.62 | KIF11 (0.74) | KIF11MAOA | |
| SCHEMBL6558942 | 0.62 | KCNN4 (0.39) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |