SCHEMBL655858

SCHEMBL655858

Nc1nc2c(nc(N)n2[C@H]2CC(O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PNP P00491 5/20 0.65
ADRB1 P08588 1/20 0.46
DNMT1 P26358 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
POLB P06746 1/20 0.45
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TK1 P04183 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.42
PDE4D Q08499 1/20 0.42
PDE3A Q14432 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL655857 1.00 PNP (0.65) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL114652 0.90 PNP (0.55) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL21779018 0.90 PNP (0.55) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL195548 0.90 PNP (0.55) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL13351290 0.89 PNP (0.54) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL13318964 0.89 PNP (0.54) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL18723297 0.89 PNP (0.54) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL18952860 0.89 PNP (0.54) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL3868526 0.89 PNP (0.54) PNPADRB1DNMT1CYP3A4MAPT
SCHEMBL14543297 0.89 PNP (0.54) PNPADRB1DNMT1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
US-20240182906-A1 GENOME EDITING USING EFFECTOR OLIGONUCLEOTIDES FOR THERAPEUTIC TREATMENT Research Foundation to Cure AIDS, Inc. (US) 2024-06-06 US disclosed
US-20240117337-A1 METHODS AND POLYNUCLEOTIDES FOR AMPLIFYING A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-04-11 US disclosed
US-20240076719-A9 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-03-07 US disclosed
US-20230295694-A1 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-09-21 US disclosed
US-11725205-B2 Methods and polynucleotides for amplifying a target polynucleotide OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-15 US disclosed
US-20230250474-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-10 US disclosed
WO-2023147565-A2 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS Opentrons LabWorks Inc. (US) 2023-08-03 WO disclosed
EP-2242761-A1 METHOD OF MYCOTOXIN DETECTION Neoventures Biotechnology Inc. (CA) 2010-10-27 EP disclosed
WO-2009086621-A1 METHOD OF MYCOTOXIN DETECTION NEOVENTURES BIOTECHNOLOGY INC. (CA) 2009-07-16 WO disclosed
US-20060008813-A1 Compositions and methods of synthesis and use of novel nucleic acid structures ERITJA RAMON 2006-01-12 US disclosed
EP-1228243-A4 COMPOSITIONS AND METHODS OF SYNTHESIS AND USE OF NOVEL NUCLEIC ACID STRUCTURES CYGENE INC (US) 2005-07-20 EP disclosed
US-20050014164-A1 Triplex-forming oligonucleotides containing modified purines and their applications ERITJA RAMON (ES) 2005-01-20 US disclosed
US-6831072-B2 Such as 8-amino-2'deoxyadenosine by treating 8-azido-2'deoxyadenosine with aqueous solution of methylamine or dimethylamine; for targeting nucleic acids without amplification and less use of enzymes CYGENE, INC. 2004-12-14 US disclosed
WO-2004037981-A2 TRIPLEX-FORMING OLIGONUCLEOTIDES CONTAINING MODIFIED PURINES AND THEIR APPLICATIONS CYGENE LABORATORIES, INC. (US) 2004-05-06 WO disclosed
US-20030135040-A1 Compositions and methods of synthesis and use of novel nucleic acid structures CYGENE, INC. 2003-07-17 US disclosed
EP-1228243-A1 COMPOSITIONS AND METHODS OF SYNTHESIS AND USE OF NOVEL NUCLEIC ACID STRUCTURES Cygene, Inc. (US) 2002-08-07 EP disclosed
WO-2001032924-A1 COMPOSITIONS AND METHODS OF SYNTHESIS AND USE OF NOVEL NUCLEIC ACID STRUCTURES CYGENE, INC. (US) 2001-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM PNP 8/4885ADRB1 4500/4885DNMT1 274/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 PNP 487/4885ADRB1 2217/4885DNMT1 1090/4885
US-20030135040-A1 Compositions and methods of synthesis and use of novel nucleic acid structures ADAR, NSUN2, RNGTT PNP 63/4885ADRB1 4785/4885DNMT1 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.